Interferometric near-infrared spectroscopy directly quantifies optical field dynamics in turbid media
نویسندگان
چکیده
DAWID BORYCKI, OYBEK KHOLIQOV, AND VIVEK J. SRINIVASAN* Department of Biomedical Engineering, University of California Davis, California 95616, USA Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University, Grudziadzka 5, 87-100 Torun, Poland Present address: Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland *Corresponding author: [email protected]
منابع مشابه
Interferometric Near-Infrared Spectroscopy (iNIRS) for determination of optical and dynamical properties of turbid media.
We introduce and implement interferometric near-infrared spectroscopy (iNIRS), which simultaneously extracts optical and dynamical properties of turbid media through analysis of a spectral interference fringe pattern. The spectral interference fringe pattern is measured using a Mach-Zehnder interferometer with a frequency-swept narrow linewidth laser. Fourier analysis of the detected signal is ...
متن کاملReflectance-mode interferometric near-infrared spectroscopy quantifies brain absorption, scattering, and blood flow index in vivo.
Interferometric near-infrared spectroscopy (iNIRS) is a new technique that measures time-of-flight- (TOF-) resolved autocorrelations in turbid media, enabling simultaneous estimation of optical and dynamical properties. Here, we demonstrate reflectance-mode iNIRS for noninvasive monitoring of a mouse brain in vivo. A method for more precise quantification with less static interference from supe...
متن کاملInterferometric near-infrared spectroscopy (iNIRS): performance tradeoffs and optimization
Interferometric near-infrared spectroscopy (iNIRS) is a time-of-flight(TOF-) resolved sensing modality for determining optical and dynamical properties of a turbid medium. iNIRS achieves this by measuring the interference spectrum of light traversing the medium with a rapidly tunable, or frequency-swept, light source. Thus, iNIRS system performance critically depends on the source and detection...
متن کاملNear-infrared photon time-of-flight spectroscopy of turbid materials up to 1400 nm.
Photon time-of-flight spectroscopy (PTOFS) is a powerful tool for analysis of turbid materials. We have constructed a time-of-flight spectrometer based on a supercontinuum fiber laser, acousto-optical tunable filtering, and an InP/InGaAsP microchannel plate photomultiplier tube. The system is capable of performing PTOFS up to 1400 nm, and thus covers an important region for vibrational spectros...
متن کاملTime reversal optical tomography: locating targets in a highly scattering turbid medium
A time reversal optical tomography (TROT) method for near-infrared (NIR) diffuse optical imaging of targets embedded in a highly scattering turbid medium is presented. TROT combines the basic symmetry of time reversal invariance and subspace-based signal processing for retrieval of target location. The efficacy of TROT is tested using simulated data and data obtained from NIR imaging experiment...
متن کامل